Circulating Biomarkers of Collagen Metabolism in Cardiac Diseases

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Circulating biomarkers of collagen metabolism in cardiac diseases.

Alterations of the structure and composition of cardiomyocyte and noncardiomyocyte compartments of the myocardium appear to play a central role in the pathogenesis of heart failure (HF) associated with a number of cardiac diseases. Among these alterations, changes in the quantity and quality of the extracellular matrix, including the collagen network, have been characterized that induce remodel...

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Alterations of the structure and composition of cardiomyocyte and noncardiomyocyte compartments of the myocardium appear to play a central role in the pathogenesis of heart failure (HF) associated with a number of cardiac diseases. Among these alterations, changes in the quantity and quality of the extracellular matrix, including the collagen network, have been characterized that induce remodel...

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ژورنال

عنوان ژورنال: Circulation

سال: 2010

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.109.912774